I recently bought 76057 Spider-Man: Web Warriors Ultimate Bridge Battle at a great deal (thanks Marco!). With the money I saved I decided to bricklink some extra foes like Sandman, The Vulture, Venom and Doctor Octopus to complete my LEGO Spider-Man minifigure collection.
This little vignette with a giant hand from sand that abviously takes inspiration from 76037 Rhino and Sandman Super Villain Team-up can very easily be incorparated into any LEGO surrounding. Just have a look at these pictures.
Piece 15535 (Flat Tile 2X2 Round W. Hole) in the palm of the giant hand allows a clever connection with a minifigure wearing piece 42446 (Mini Fig. Back Palte W. Knob) around his neck.